42. Why do universal longevity interventions often involve tradeoffs?

Universal interventions shift global allocation or operating conditions (growth, reproduction, repair, metabolism), so benefits in lifespan can come with costs in performance or fitness-relevant traits. This is expected if species are locally optimized: pushing lifespan beyond the evolved optimum requires rebalancing constraints across the whole organism. In practice, this often appears as side effects, reduced resilience in particular contexts, or diminished capacity under stress. Organismal tradeoffs may be expected in the case of organ/system-specific interventions and other approaches.